Human BAI3 (NP_001695) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human BAI3 (NP_001695) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: BAI3

BAI3 (Brain angiogenesis inhibitor 3) is an adhesion GPCR that plays a role in neuronal synapse formation and maintenance. It is primarily expressed post-synaptically in the cerebral cortex and on cerebellar Purkinje cells, and it binds to the TNF-like proteins C1qL1, 2, 3, and 4. BAI3 interaction with C1qL1 is required for the formation and maintenance of excitatory synapses between climbing fibers and parallel fibers with Purkinje cells. BAI3 ligation can also reduce excitatory synaptic density in hippocampal neurons, decrease dendrite arborization, and promote axon pruning in climbing fibers. It is additionally expressed in developing muscle where it is required for myoblast fusion.

Long Name
Brain-specific Angiogenesis Inhibitor 3
Entrez Gene IDs
577 (Human); 210933 (Mouse); 301309 (Rat)
Alternate Names
BAI3; brain-specific angiogenesis inhibitor 3; dJ91B17.1 (brain-specific angiogenesis inhibitor 3); KIAA0550MGC133100


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