Human C4.4A/LYPD3 (NP_055215) VersaClone cDNA

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Human C4.4A/LYPD3 (NP_055215) VersaClone cDNA
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Product Details

Human C4.4A/LYPD3 (NP_055215) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: C4.4A/LYPD3

C4.4A, also known as LYPD3, is a 65-100 kDa GPI-linked glycoprotein with structural similarity to uPAR. Soluble forms are generated by proteolytic cleavage or released in membrane vesicles. C4.4A is expressed in the suprabasal layers of stratified squamous epithelium, and it is upregulated at the invasive front of melanomas and carcinomas. Metastases derived from these tumors also express high levels of C4.4A. The interaction of C4.4A with Laminin-1 and -5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells.

Long Name
Leucine Rich Repeat and Fibronectin Type III Domain Containing 3
Entrez Gene IDs
27076 (Human); 72434 (Mouse); 60378 (Rat)
Alternate Names
C4.4A; C4.4A2310061G07Rik; GPI-anchored metastasis-associated protein C4.4A homolog; GPI-anchored metastasis-associated protein homolog; LY6/PLAUR domain containing 3; ly6/PLAUR domain-containing protein 3; LYPD3; Matrigel-induced gene C4 protein; MIG-C4


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