Human Cathepsin K (NP_000387.1) VersaClone cDNA

Name: Human Cathepsin K (NP_000387.1) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3364
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC3364

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_000387.1

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Cathepsin K

Cathepsin K is encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Alternate Names

CTS02, CTSK, CTSO1, CTSO2, PKND, PYCD

Entrez Gene IDs

1513 (Human); 13038 (Mouse); 29175 (Rat)

Gene Symbol

CTSK

UniProt

NP_000387.1 (Human)

Additional Cathepsin K Products

Product Documents for Human Cathepsin K (NP_000387.1) VersaClone cDNA

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Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Cathepsin K (NP_000387.1) VersaClone cDNA

For research use only

Related Research Areas

Cysteine Proteases and Regulators

Lysosomal Enzymes

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