Human CD1d (NP_001757) VersaClone cDNA Summary
CD1d1 is a 48 kDa transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. Complexes of CD1d1 with beta 2-microglobulin and endogenous glycolipids are constitutively expressed on antigen presenting cells, cortical thymocytes, liver sinusoidal endothelial cells, Kupffer cells, and hepatocytes. CD1d1-presented glycolipids are recognized by canonical NKT cells that utilize an invariant mouse V alpha 14-J alpha 18 chain in their T cell receptor (V alpha 24-J alpha 18 in human). The interaction with glycolipid-loaded CD1d1 is critical for NKT cell development and induces their rapid secretion of both Th1 and Th2 type cytokines. In humans, infection with HSV-1 suppresses NKT cell activation by blocking the intracellular cycling of CD1d1 in antigen presenting cells.
No product specific FAQs exist for this product, however you mayView all cDNA Clone FAQs
Reviews for Human CD1d (NP_001757) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human CD1d (NP_001757) VersaClone cDNA and earn rewards!
Have you used Human CD1d (NP_001757) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image