Human CD52 (Research Grade Alemtuzumab Biosimilar) Antibody
Human CD52 (Research Grade Alemtuzumab Biosimilar) Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of CD52 in human PBMC lymphocytes by Flow Cytometry. Human PBMC lymphocytes were stained with Human Anti-Human CD52 (Alemtuzumab Biosimilar) Monoclonal Antibody (Catalog # MAB9889, filled histogram) or no primary antibody (open histogram) followed by APC-conjugated Anti-Human IgG Secondary Antibody (Catalog # F0135). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Alemtuzumab is a biosimilar directed against the extracellular domain of CD52. The biotinylated antibody (catalog number FAB9889B) can be used in flow cytometry or various assay format to measure CD52 expression and can be detected by conjugated streptavidin.
Citation for Human CD52 (Research Grade Alemtuzumab Biosimilar) Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation
Authors: P Shafiei-Ja, DG Helou, BP Hurrell, L Galle-Treg, E Howard, C Quach, JD Painter, M Fung, R Lo, H Allayee, O Akbari
Mucosal Immunology, 2021;0(0):.
Sample Types: In Vivo
Does this Biosimilar antibody have the same sequence as the therapeutic antibody?
The Biosimilar antibody has the same variable region and constant region sequence as the therapeutic antibody.
What is a Biosimilar antibody?
A Biosimilar antibody is a non-therpeutic, recombinantly-expressed antibody which has the same sequence as the corresponding therapeutic antibody. It is for research use only. The nomenclature of the Biosimilar antibody includes the name of the therapeutic antibody. For example, Catalog # MAB9577 is called Human EGFR (Research Grade CetuxiMab Biosimilar) antibody.
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