Human CD8+ T Cell Enrichment Column, Small, Pack of 4

R&D Systems | Catalog # HCD8C-1000

R&D Systems
Discontinued Product
HCD8C-1000 has been discontinued. An alternative/replacement product is available: MAGH112. View all CD8 products.

Key Product Details

Species

Human
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Background: CD8

CD8, also known as Ly-2 or Leu-2, is a heterodimeric glycoprotein (alpha and beta subunits) that functions in conjunction with the T cell receptor in the recognition of MHC class I/peptide complexes. CD8 alpha is expressed on double positive (CD4+8+) thymocytes and mature CD8+ cytolytic T cells, intraepithelial lymphocytes, some gamma-delta T cells, subsets of thymic and splenic dendritic cells, and peritoneal mast cells. It can form disulfide linked homodimers or heterodimers with CD8 beta. Thymic CD8+ DC express primarily alpha-beta heterodimers, while splenic CD8+ DC primarily express alpha-alpha homodimers. CD8 alpha+ DC can present viral antigenic peptides in complex with MHC I and prime CTL responses.

Alternate Names

CD8, CD8A

Entrez Gene IDs

925 (Human); 12525 (Mouse); 24930 (Rat); 102124337 (Cynomolgus Monkey); 493799 (Feline)

Gene Symbol

CD8A

Additional CD8 Products

Product Documents for Human CD8+ T Cell Enrichment Column, Small, Pack of 4

Certificate of Analysis

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Product Specific Notices for Human CD8+ T Cell Enrichment Column, Small, Pack of 4

For research use only

Citations for Human CD8+ T Cell Enrichment Column, Small, Pack of 4

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    Name: Leslie Priddy
    Verified Customer | Posted 04/20/2018

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