Human CILP-1 (AAH35776) VersaClone cDNA

Name: Human CILP-1 (AAH35776) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2714
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC2714

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

AAH35776

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: CILP-1

CILP, Cartilage Intermediate Layer Protein, is specifically expressed in the articular cartilage intermediate layer (it cannot be found in the superficial nor in the deepest layers) and is involved in scaffolding. Overexpression of this protein may lead to impairment of chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. Antibodies against CILP are detected in patients with early-stage knee osteoarthritis and defects in this gene may be a cause of susceptibility to lumbar disk disease.

Long Name

Cartilage Intermediate Layer Protein 1

Alternate Names

CILP, CILP1

Entrez Gene IDs

8483 (Human); 214425 (Mouse); 315761 (Rat)

Gene Symbol

CILP

UniProt

AAH35776

Additional CILP-1 Products

Product Documents for Human CILP-1 (AAH35776) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human CILP-1 (AAH35776) VersaClone cDNA

For research use only

Related Research Areas

Extracellular Matrix Molecules

IGF Family

Metabolic Peptide Hormones and Regulators

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