The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.
Human Common beta Chain (NP_000386) VersaClone cDNA
R&D Systems | Catalog # RDC1170
Loading...
Loading...
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Common beta Chain
Alternate Names
CD131, CSF2RB, GM-CSF R beta, IL-3 R beta, IL-5 R beta
Gene Symbol
CSF2RB
UniProt
Additional Common beta Chain Products
Product Documents for Human Common beta Chain (NP_000386) VersaClone cDNA
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Common beta Chain (NP_000386) VersaClone cDNA
For research use only
Customer Reviews for Human Common beta Chain (NP_000386) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human Common beta Chain (NP_000386) VersaClone cDNA and earn rewards!
Have you used Human Common beta Chain (NP_000386) VersaClone cDNA?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...
Associated Pathways
