Human DAP10/HCST Alexa Fluor® 405-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB9786V-100UG
R&D Systems Antibodies
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Human DAP10/HCST Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human DAP10/HCST in direct ELISAs.
Source
Monoclonal Mouse IgG2A Clone # 982129
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Synthetic peptide containing human DAP10/HCST
Accession # Q9UBK5
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
U937 Human Histiocytic Lymphoma Cell Line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: DAP10/HCST

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Entrez Gene IDs
10870 (Human); 23900 (Mouse); 474146 (Rat)
Alternate Names
DAP10; DAP10PIK3AP; DKFZP586C1522; HCST; hematopoietic cell signal transducer; KAP10; KAP10DNAX-activation protein 10; kinase assoc pro of ~10kDa; Kinase Assoc Protein; Membrane protein DAP10; phosphoinositide-3-kinase adaptor protein; PIK3AP; Transmembrane adapter protein KAP10

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