Human DAP10/HCST (NP_055081) VersaClone cDNA

R&D Systems | Catalog # RDC2544

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Background: DAP10/HCST

HCST encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Alternate Names

HCST, KAP10, Kinase Assoc Protein, PIK3AP

Entrez Gene IDs

10870 (Human); 23900 (Mouse); 474146 (Rat)

Gene Symbol

HCST

UniProt

Additional DAP10/HCST Products

Product Documents for Human DAP10/HCST (NP_055081) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human DAP10/HCST (NP_055081) VersaClone cDNA

For research use only

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