Human DCIR/CLEC4A (NP_057268) VersaClone cDNA Summary
DCIR, also known as lectin-like immunoreceptor (LLIR), is a type II transmembrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. DCIR is expressed on dendritic cells, B cells, monocytes/macrophages and granulocytes.
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