Human delta-Sarcoglycan (NP_001121681.1) VersaClone cDNA Summary
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delta-Sarcoglycan is a 35-kDa type II transmembrane glycoprotein that participates in sarcoglycan complex formation. This complex is formed sequentially and consists of five (alpha- through epsilon-) Sarcoglycan subunits. The initial step involves delta-sarcoglycan binding to beta-Sarcoglycan, followed by the addition of alpha-, gamma-, and epsilon-Sarcoglycan. delta-Sarcoglycan is necessary for early complex stability. The sarcoglycan complex interacts with a cell surface dystrophin complex to link the cytoskeleton to the extracellular matrix.
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