Human DGK-iota (NP_004708) VersaClone cDNA

R&D Systems | Catalog # RDC2054

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: DGK-iota

DGK (Diacylglycerol kinase alpha) proteins are type I members of the eukaryocytic diacylglycerol kinase family of enzymes, possessing EF-hand, C1/Cys-rich zinc finger and catalytic domains. DGK-alpha in IL-2-stimulated T cells translocates to the nucleus, promoting proliferation. TCR stimulation, however, promotes anergy. DGK-alpha also participates in VEGF or HGF-mediated motility in endothelial, epithelial, or cancer cells. DGK-gamma is highly enriched in the retina and cerebellar Purkinje cells, and presence of unactivated protein in the nucleus may regulate the cell cycle.

Long Name

Diacylglycerol Kinase, iota 64kDa

Alternate Names

DGKI, DGKiota

Entrez Gene IDs

9162 (Human); 320127 (Mouse); 688705 (Rat)

Gene Symbol

DGKI

UniProt

Additional DGK-iota Products

Product Documents for Human DGK-iota (NP_004708) VersaClone cDNA

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human DGK-iota (NP_004708) VersaClone cDNA

For research use only

Related Research Areas

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