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Human EBI2 (NP_004942) VersaClone cDNA

Catalog #: RDC0219 Datasheet / COA / SDS
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RDC0219
R&D Systems VersaClone cDNA Plasmids
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Human EBI2 (NP_004942) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: EBI2

EBI2 was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. EBI2 is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor and signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha. EBI2 is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. EBI2 is an orphan receptor that plays a central role during humoral immunity and promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses.

Long Name
Epstein-Barr Virus Induced Gene 2
Entrez Gene IDs
1880 (Human); 321019 (Mouse); 679975 (Rat)
Alternate Names
EBI2; EBI2Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupledreceptor); EBV-induced G-protein coupled receptor 2; Epstein-Barr virus-induced G-protein coupled receptor 2; G protein-coupled receptor 183; GPR183; G-protein coupled receptor 183

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Tocris Small Molecules

NIBR 189

5203
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