Human EBI2 (NP_004942) VersaClone cDNA Summary
EBI2 was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. EBI2 is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor and signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha. EBI2 is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. EBI2 is an orphan receptor that plays a central role during humoral immunity and promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses.
No product specific FAQs exist for this product, however you mayView all cDNA Clone FAQs
Tocris Small Molecules
Reviews for Human EBI2 (NP_004942) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human EBI2 (NP_004942) VersaClone cDNA and earn rewards!
Have you used Human EBI2 (NP_004942) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image