Human ENPP‑3/CD203c APC‑conjugated Antibody

R&D Systems | Catalog # FAB5756A

R&D Systems
Discontinued Product
FAB5756A has been discontinued. View all ENPP-3/CD203c products.

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # NP4D6
View all ENPP-3/CD203c Primary Antibodies »

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human ENPP‑3/CD203c
Accession # O14638

Specificity

Detects human ENPP‑3/CD203c.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human ENPP‑3/CD203c APC‑conjugated Antibody

Detection of ENPP-3/CD203c antibody in Human Whole Blood Lymphocytes and Monocytes antibody by Flow Cytometry.

Detection of ENPP‑3/CD203c in Human Whole Blood Lymphocytes and Monocytes by Flow Cytometry.

Human whole blood lymphocytes and monocytes were stained with Mouse Anti-Human IL-3 Ra/CD123 PE-conjugated Monoclonal Antibody (Catalog # FAB301P) and either (A) Mouse Anti-Human ENPP-3/CD203c APC-conjugated Monoclonal Antibody (Catalog # FAB5756A) or (B) Mouse IgG1Allophycocyanin Isotype Control (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human ENPP‑3/CD203c APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human whole blood lymphocytes and monocytes

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: ENPP-3/CD203c

CD203c is a 120-130 kDa type II transmembrane glycoprotein that belongs to the ectonucleotidase family, AP superfamily of enzymes. CD203c is also known as ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP-3) and it modulates purinergic signaling by hydrolysis of nucleotide di- and tri-phosphates plus sphingosylphosphorylenosine. Although CD203c is considered to be a marker for activated basophils and mast cells, it is also found constitutively or inducibly on bile duct epithelium, hepatocytes, duodenal columnar epithelium, osteoblasts, plasmacytoid dendritic cells, airway pseudostratified ciliated columnar epithelium and renal proximal tubule S3 segment cells. Within the ECD, human CD203c shares 81% aa sequence identity with mouse and rat CD203.

Long Name

Ectonucleotide Pyrophosphatase/Phosphodiesterase 3

Alternate Names

B10, CD203c, ENPP3, NPP3, PD-IBETA, PDNP3

Entrez Gene IDs

5169 (Human)

Gene Symbol

ENPP3

UniProt

O14638

Additional ENPP-3/CD203c Products

Product Documents for Human ENPP‑3/CD203c APC‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human ENPP‑3/CD203c APC‑conjugated Antibody

For research use only

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