Human ENPP-4 (NP_055751) VersaClone cDNA

R&D Systems | Catalog # RDC2437

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ENPP-4

ENPP-4 (Ectonucleotide pyrophosphatase/phosphodiesterase 4; NPP4) belongs to a group of ecto-enzymes which regulate the availability of extracellular nucleotides. ENPP-4 hydrolyzes phosphodiester bonds in nucleotides with a preference for adenine nucleotides. It cleaves the diadenosine compounds Ap3A and Ap4a which are released from the dense granules of thrombin-activated platelets. These reactions generate AMP and ADP from Ap3A cleavage, and AMP and ATP from Ap4A cleavage. ENPP-4 is expressed on the surface of vascular endothelial cells where its activity prolongs platelet aggretation and contributes to thrombus formation.

Long Name

Ectonucleotide Pyrophosphatase/Phosphodiesterase 4

Alternate Names

AP3Aase, ENPP4, NPP-4

Entrez Gene IDs

22875 (Human); 224794 (Mouse); 301261 (Rat)

Gene Symbol

ENPP4

UniProt

Additional ENPP-4 Products

Product Documents for Human ENPP-4 (NP_055751) VersaClone cDNA

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human ENPP-4 (NP_055751) VersaClone cDNA

For research use only

Related Research Areas

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