Human Erythropoietin R (NP_000112) VersaClone cDNA

Name: Human Erythropoietin R (NP_000112) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1158
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC1158

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_000112

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Erythropoietin R

Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

Long Name

Erythropoietin Receptor

Alternate Names

EpoR

Entrez Gene IDs

2057 (Human); 13857 (Mouse)

Gene Symbol

EPOR

UniProt

NP_000112

Additional Erythropoietin R Products

Product Documents for Human Erythropoietin R (NP_000112) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human Erythropoietin R (NP_000112) VersaClone cDNA

For research use only

Related Research Areas

Endothelial Cell Markers

Hematopoietic Stem Cell Markers

Red Blood Cells (RBCs)

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