Human ETV5 Alexa Fluor™ Plus 555‑conjugated Antibody

R&D Systems | Catalog # FAB7107AFP555

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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

Alexa Fluor Plus 555 (Excitation = 558 nm, Emission = 572 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 654404
View all ETV5 Primary Antibodies »

Product Specifications

Specificity

Detects human ETV5 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ETV1 or rhETV2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human ETV5 Alexa Fluor™ Plus 555‑conjugated Antibody

Application
Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ETV5

ETS translocation variant 5 (ETV5), also known as ERM, is an approximately 70 kDa member of the ETS transcription factor family. The expression of ETV5 in Sertoli, granulosa, and cumulus cells is important for the ability of these cells to support spermatogonia stem cell and oocyte development. ETV5 is upregulated at the invasive front of various carcinomas, and it plays a role in tumor cell invasiveness. It is a target of chromosomal translocation in prostate cancer and forms a fusion protein with TMPRSS2. It is also required for branching morphogenesis during early kidney development. ETV5 contains a single Ets DNA-binding domain (aa 367-452). Within aa 119-223, human ETV5 shares 92% aa sequence identity with mouse and rat ETV5.

Long Name

ETS Translocation Variant 5

Alternate Names

ERM

Entrez Gene IDs

2119 (Human); 104156 (Mouse); 303828 (Rat)

Gene Symbol

ETV5

UniProt

P41161

Additional ETV5 Products

Product Documents for Human ETV5 Alexa Fluor™ Plus 555‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human ETV5 Alexa Fluor™ Plus 555‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

ETS Family Transcription Factors

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