Forkhead Box P1 (FOXP1) is a member of the FOX family of transcription factors. FoxP1 has been implicated in cardiac, lung, and lymphocyte development. FoxP1 knock out mice die at embryonic day 14.5 due to heart valve and outflow tract abnormalities. FoxP1 contains both a DNA binding domain as well as protein-protein interaction domains. FoxP1 can homo or heterodimeize with FoxP2 and FoxP4, with dimerization necessary for DNA binding. FoxP1 shows both oncogenic and tumor suppressive characteristics. Overexpression in lymphomas leads to poor prognosis, whereas, loss of FoxP1 in breast cancer also implicates a poor prognosis.
Human FoxP1 (NP_116071) VersaClone cDNA
R&D Systems | Catalog # RDC1703
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: FoxP1
Long Name
Forkhead Box P1
Alternate Names
QRF1
Gene Symbol
FOXP1
UniProt
Additional FoxP1 Products
Product Documents for Human FoxP1 (NP_116071) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human FoxP1 (NP_116071) VersaClone cDNA
For research use only
Related Research Areas
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