Human FPRL1/FPR2 Alexa Fluor® 405-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3479V-100UG
Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry.
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Human FPRL1/FPR2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Stains FPRL1 transfectants but not irrelevant transfectants. It also stains monocytes and granulocytes.
Source
Monoclonal Mouse IgG2B Clone # 304405
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human FPRL1
Met1-Met351
Accession # P25090
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 405

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry. View Larger

Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human FPRL1/FPR2 Alexa Fluor® 405‑conjugated Monoclonal Antibody (Catalog # FAB3479V, filled histogram) or isotype control antibody (Catalog # IC0041V, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FPRL1/FPR2

FPRL1 is a 7TM protein expressed on mononuclear phagocytes and microglial cells. It interacts with formyl peptides to attract phagocytes to sites of infection and promote inflammatory reactions. FPRL1 also interacts with amyloid beta peptides and has been implicated in phagocyte attraction to sites of amyloid plaques in Alzheimer’s disease.

Long Name
Formyl Peptide Receptor-like 1
Entrez Gene IDs
2358 (Human); 14289 (Mouse)
Alternate Names
ALXR; FMLP-R-I; FMLP-R-II; FMLPX; formyl peptide receptor 2; Formyl peptide receptor-like 1RFP; FPR2; FPR2A; FPRH1FMLP-related receptor I; FPRL1; FPRL1LXA4 receptor; HM63; HM63FPRH2; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin A4 receptor; LXA4 Receptor; LXA4RFMLP-R-I; N-formyl peptide receptor 2; RFP

Product Datasheets

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