Human FPRL1/FPR2 Fluorescein-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3479F
Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry.
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Citations (4)
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Human FPRL1/FPR2 Fluorescein-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Stains FPRL1/FPR2 transfectants but not irrelevant transfectants. It also stains monocytes and granulocytes.
Source
Monoclonal Mouse IgG2B Clone # 304405
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human FPRL1/FPR2
Met1-Met351
Accession # P25090
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of FPRL1/FPR2 antibody in Human Blood Monocytes antibody by Flow Cytometry. View Larger

Detection of FPRL1/FPR2 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human FPRL1/FPR2 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB3479F, filled histogram) or isotype control antibody (Catalog # IC0041F, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FPRL1/FPR2

FPRL1, also known as FPR2, is a 7TM protein expressed on mononuclear phagocytes and microglial cells. It interacts with formyl peptides to attract phagocytes to sites of infection and promote inflammatory reactions. FPRL1 also interacts with amyloid beta peptides and has been implicated in phagocyte attraction to sites of amyloid plaques in Alzheimer’s disease.

Long Name
Formyl Peptide Receptor-like 1
Entrez Gene IDs
2358 (Human); 14289 (Mouse)
Alternate Names
ALXR; FMLP-R-I; FMLP-R-II; FMLPX; formyl peptide receptor 2; Formyl peptide receptor-like 1RFP; FPR2; FPR2A; FPRH1FMLP-related receptor I; FPRL1; FPRL1LXA4 receptor; HM63; HM63FPRH2; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin A4 receptor; LXA4 Receptor; LXA4RFMLP-R-I; N-formyl peptide receptor 2; RFP

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Citations for Human FPRL1/FPR2 Fluorescein-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. BDNF-dependent modulation of axonal transport is selectively impaired in ALS
    Authors: AP Tosolini, JN Sleigh, S Surana, ER Rhymes, SD Cahalan, G Schiavo
    Acta neuropathologica communications, 2022;10(1):121.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  2. Suppression of annexin A1 and its receptor reduces herpes simplex virus 1 lethality in mice
    Authors: LC Wang, SR Wu, HW Yao, P Ling, GC Perng, YC Chiu, SM Hsu, SH Chen
    PloS Pathogens, 2022;18(8):e1010692.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. 15-Epi-LXA4 and 17-epi-RvD1 restore TLR9-mediated impaired neutrophil phagocytosis and accelerate resolution of lung inflammation
    Authors: M Sekheri, D El Kebir, N Edner, JG Filep
    Proc. Natl. Acad. Sci. U.S.A., 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway
    Authors: Y Yang, H Choi, M Seon, D Cho, SI Bang
    Stem Cell Res Ther, 2016;7(1):58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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