|Detection of FPRL2/FPR3 in NS0 Mouse Cell Line with Human FPRL2/FPR3 and eGFP by Flow Cytometry. NS0 mouse myeloma cell line transfected with human FPRL2/FPR3 and eGFP was stained with Mouse Anti-Human FPRL2/FPR3 APC‑conjugated Monoclonal Antibody (Catalog # FAB3896A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.|
FPRL2 (Formyl Peptide Receptor-like 2), also known as FPR3 and FMLP receptor-like 2, is a 64-68 kDa 7TM protein that is expressed on monocytes and dendritic cells. It interacts with formyl and acetyl peptides to attract these cells to sites of infection. FPRL2 signaling also inhibits DC maturation. Human FPRL2 shares 63% and 62% amino acid sequence identity with mouse and rat FPRL2, respectively.
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