FYB, also known as ADAP and SLAP130, is a 130 kDa hematopoietic-specific adaptor protein which contains an SH3-VASP homology 1 domain. It associates with other cytoplasmic proteins such as SH2-containing Leukocyte Phosphoprotein of 76 kDa (SLP-76). SLAP130 is phosphorylated in response to TCR/CD3 stimulation, and regulates the stability of SKAP55. A SLAP130:SKAP55 signaling module stimulates beta 1 and beta 2 integrin activation and promotes T cell-DC cell interaction.
Human FYB/ADAP/SLAP130 (NP_955367) VersaClone cDNA
R&D Systems | Catalog # RDC1173
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: FYB/ADAP/SLAP130
Long Name
FYN Binding Protein (FYB-120/130)
Alternate Names
ADAP, PRO0823, SLAP130
Gene Symbol
FYB1
UniProt
Additional FYB/ADAP/SLAP130 Products
Product Documents for Human FYB/ADAP/SLAP130 (NP_955367) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human FYB/ADAP/SLAP130 (NP_955367) VersaClone cDNA
For research use only
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