GFR alpha -1, -2, -3, and -4 are GPI-anchored receptors that interact preferentially with the GDNF family ligands GDNF, Neurturin, Artemin, and Persephin, respectively. GFR alpha proteins initiate signaling in association with the receptor tyrosine kinase RET and by RET-independent pathways. GFR alpha-mediated signaling is instrumental in the differentiation, migration, and support of central and peripheral neurons. Alternative splicing generates multiple isoforms of GFR alpha proteins.
Human GFR alpha-4 (NP_665705) VersaClone cDNA
R&D Systems | Catalog # RDC1590
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: GFR alpha-4/GDNF R alpha-4
Long Name
Glial Cell line-derived Neurotrophic Factor Receptor alpha 4
Alternate Names
GDNF R alpha-4, GFR alpha4, GFRa-4, GFRA4
Gene Symbol
GFRA4
UniProt
Additional GFR alpha-4/GDNF R alpha-4 Products
Product Documents for Human GFR alpha-4 (NP_665705) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human GFR alpha-4 (NP_665705) VersaClone cDNA
For research use only
Related Research Areas
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