Human GKAP/DLGAP1 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB7296R Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB7296R-100UG

All GKAP/DLGAP1 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human GKAP/DLGAP1 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human GKAP in direct ELISAs.

Source

Monoclonal Mouse IgG2b Clone # 727425

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human GKAP
Lys368-Glu472
Accession # O14490

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GKAP/DLGAP1

GKAP, also known as DAP1, DLGAP, and SAPAP1, is an approximately 45 kDa cytoplasmic membrane associated protein. GKAP is a component of a neuronal postsynaptic complex that also includes PSD-95 and SHANK. This complex links neurotransmitter channels with the cytoskeleton and can promote NMDA R channel opening. Alternate splice forms of human GKAP have N-terminal and/or C-terminal truncations and are differentially expressed during brain development. Within aa 368-472 human, mouse, and rat GKAP share 100% aa sequence identity.

Long Name

Guanylate Kinase-associated Protein

Entrez Gene IDs

9229 (Human); 224997 (Mouse); 65040 (Rat)

Alternate Names

DAP1; DAP-1-ALPHA; DAP-1DAP-1-BETA; discs, large (Drosophila) homolog-associated protein 1; disks large-associated protein 1; DLGAP1; GKAP; GKAPMGC88156; hGKAP; PSD-95/SAP90 binding protein 1; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1; SAPAP1Guanylate kinase-associated protein