GPR177, also known as WLS, belongs to the wntless family of proteins and interacts with Wnt-1, Wnt-3, Wnt-3a and Wnt-5a. WLS regulates Wnt protein sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. WLS plays an important role in establishment of the anterior-posterior body axis formation during development.
Human GPR177/WLS (NP_079187) VersaClone cDNA
R&D Systems | Catalog # RDC0212
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Background: GPR177/WLS
Alternate Names
C1orf139, Evi, Sprinter, WLS, Wntless
Gene Symbol
WLS
UniProt
Additional GPR177/WLS Products
Product Documents for Human GPR177/WLS (NP_079187) VersaClone cDNA
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Product Specific Notices for Human GPR177/WLS (NP_079187) VersaClone cDNA
For research use only
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