Human GRAIL/RNF128 (NP_919445.1) VersaClone cDNA

R&D Systems | Catalog # RDC3472

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Key Product Details

Species

Human

Accession Number

NP_919445.1

Background: GRAIL/RNF128

The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Long Name

Gene Related to Anergy in Lymphocytes Protein/Ring Finger Protein 128

Alternate Names

RNF128

Entrez Gene IDs

79589 (Human); 66889 (Mouse); 315911 (Rat)

Gene Symbol

RNF128

UniProt

NP_919445.1 (Human)

Additional GRAIL/RNF128 Products

Product Documents for Human GRAIL/RNF128 (NP_919445.1) VersaClone cDNA

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Product Specific Notices for Human GRAIL/RNF128 (NP_919445.1) VersaClone cDNA

For research use only

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