Human HTRA4 (NP_710159) VersaClone cDNA

R&D Systems | Catalog # RDC2763

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Key Product Details

Species

Human

Accession Number

NP_710159

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: HTRA4

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

Long Name

HtrA serine peptidase 4

Alternate Names

HTRA 4

Entrez Gene IDs

203100 (Human); 330723 (Mouse)

Gene Symbol

HTRA4

UniProt

NP_710159

Additional HTRA4 Products

Product Documents for Human HTRA4 (NP_710159) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human HTRA4 (NP_710159) VersaClone cDNA

For research use only

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