IFN-alpha/beta R2, also known as IFNAR2, is a 100 kDa component of the class II cytokine receptor that binds the type I interferons IFN-alpha, IFN-beta, and IFN-omega. IFN-alpha/beta R2 associates with the 125 kDa IFN-alpha/beta R1 component to form a receptor complex that transmits antiviral and antiproliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation. A soluble form of the protein, corresponding to the extracellular ligand-binding domain, is generated by alternative splicing.
Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA
R&D Systems | Catalog # RDC1361
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Background: IFN-alpha/beta R2
Long Name
Interferon alpha/beta Receptor 2
Alternate Names
IFN-aR2, IFN-bR2, IFNAR2, IFNbR2
Gene Symbol
IFNAR2
UniProt
Additional IFN-alpha/beta R2 Products
Product Documents for Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA
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Product Specific Notices for Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA
For research use only
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Associated Pathways
