Human IFN-epsilon Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB91471V Datasheet / COA / SDS

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FAB91471V-100UG

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All IFN-epsilon Antibodies

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Human IFN-epsilon Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IFN-epsilon in direct ELISAs.

Source

Monoclonal Mouse IgG2b Clone # 983303

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human IFN-epsilon
Leu22-Arg208
Accession # Q86WN2

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

ELISA

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IFN-epsilon

Interferon-epsilon (IFNe) is a type I interferon with expression limited to the brain, lung, intestine and reproductive tract. It has been proposed that unlike other type I interferons, IFNe plays a role in mucosal immunity and protects against pathogens including chlamidia, HIV and herpes simplex virus 2. Its expression is upregulated by TNF alpha. Unlike other type-1 interferons, IFNe is also hormonally regulated, and mouse and human IFNe have been shown to have a binding site in their promoters for progesterone receptor. Epithelial cells isolated from uterine endometrium have higher IFNee expression in the proliferative phase, when estrogen levels are highest. IFNe is the only IFN isoform constituitively expressed in HeLa cells.

Long Name

Interferon epsilon

Entrez Gene IDs

338376 (Human); 230405 (Mouse); 298225 (Rat)

Alternate Names

IFNE; IFN-E; IFNE1PRO655; IFNepsilon; IFN-epsilon; IFNT1; Ifn-tau-11; INFE1; interferon epsilon 1; interferon epsilon; Interferon epsilon-1; interferon tau-1; interferon, epsilon; interferon-epsilon; MGC119018; MGC119020