IL-10 mediates its biological activities via binding to a heteromeric complex of two distinct type II cytokine receptor subunits, the ligand binding subunit IL-10 R alpha (IL-10 R1) and the signal-transducing accessory subunit IL-10 R beta (IL-10 R2). IL-10 R alpha is specific for IL-10 and expressed by most hemopoietic cells. IL-10 R beta is a widely expressed shared subunit for IL-10, IL-22, IL-26 and the IFNl proteins IL-28A, IL-28B and IL-29.
Human IL-10 R beta (NP_000619) VersaClone cDNA
R&D Systems | Catalog # RDC1247
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Background: IL-10 R beta
Long Name
Interleukin 10 Receptor beta
Alternate Names
CDw210b, CRFB4, D21S58, IL-10R2, IL-10Rb, IL10R beta, IL10RB
Gene Symbol
IL10RB
UniProt
Additional IL-10 R beta Products
Product Documents for Human IL-10 R beta (NP_000619) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human IL-10 R beta (NP_000619) VersaClone cDNA
For research use only
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Associated Pathways
