Human INSL3 (NP_005534.2) VersaClone cDNA

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Human INSL3 (NP_005534.2) VersaClone cDNA
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Human INSL3 (NP_005534.2) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: INSL3

INSL3 (insulin-like 3), formerly called Ley I-L (Leydig cell insulin-like), is a member of the insulin/relaxin superfamily. INSL-3 is a secreted protein produced by testicular Leydig cells and in lower amounts by ovarian follicular theca interna cells and the corpus luteum. The receptor for INSL-3 is the leucine-rich G-protein coupled receptor LGR8, also called RXFP2 or GREAT. Deletion of either INSL3 or LGR8 in the mouse causes failure of the testes to descend (cryptorchidism). Mutation of INSL3 is also an occasional cause of cryptorchidism in humans.

Long Name
Insulin-like 3
Entrez Gene IDs
3640 (Human); 16336 (Mouse); 114215 (Rat)
Alternate Names
INSL3; insulin-like 3 (Leydig cell); insulin-like 3; Ley I-L; leydig insulin -like hormone; leydig insulin -like peptide; Leydig insulin-like peptide; Ley-I-L; MGC119818; MGC119819; relaxin-like factor b; Relaxin-like factor; RLF; RLFley-I-L; RLNL


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