Human ITIH2 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB101993R Datasheet / COA / SDS

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FAB101993R-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ITIH2 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human ITH2 in ELISA.

Source

Monoclonal Mouse IgG2a Clone # 1023637

Purification

Protein A or G purified

Immunogen

Spodoptera frugiperda Sf 9 (baculovirus)-derived human ITIH2
Ser55-Asp702
Accession # P19823

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

ELISA

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ITIH2

The ITIs are a family of plasma protease inhibitors contributing to extracellular matrix stabilization by covalent linkage to hyaluronan. ITIH2 is a binding protein between hyaluronan and other matrix proteins. It regulates the localization, synthesis and degradation of hyaluronan. ITIH molecules are shown to play a role in carcinogenesis and inflammation. ITIH genes are downregulated in multiple human solid tumors. This downregulation contributes to initiation and/or progression of malignancy.

Long Name

Inter-Alpha-Trypsin Inhibitor Heavy Chain 2

Entrez Gene IDs

3698 (Human); 16425 (Mouse)

Alternate Names

H2P; IGHEP2; Inter-Alpha (Globulin) Inhibitor H2; inter-alpha (globulin) inhibitor, H2 polypeptide; Inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor complex component II; inter-alpha-trypsin inhibitor heavy chain H2; Intin2; ITI Heavy Chain H2; ITIH2; ITI-H2; ITI-HC2; Serum-derived hyaluronan-associated protein; SHAP