Human KIR2DS2 (NP_036444) VersaClone cDNA

R&D Systems | Catalog # RDC1759

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Key Product Details

Species

Human

Accession Number

NP_036444

Background: KIR2DS2

The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.

Long Name

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 2

Alternate Names

183ActI, CD158b, CD158j, Cl-49, NKAT5, p58 NK Receptor CL-49

Entrez Gene IDs

100132285 (Human)

Gene Symbol

KIR2DS2

UniProt

NP_036444

Additional KIR2DS2 Products

Product Documents for Human KIR2DS2 (NP_036444) VersaClone cDNA

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Product Specific Notices for Human KIR2DS2 (NP_036444) VersaClone cDNA

For research use only

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