Human KLRC4/NKG2F (NP_038459.1) VersaClone cDNA

R&D Systems | Catalog # RDC3222

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Key Product Details

Species

Human

Accession Number

NP_038459.1

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: KLRC4

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq]

Long Name

Killer Cell Lectin Like Receptor C4

Alternate Names

NKG2F

Entrez Gene IDs

8302 (Human)

Gene Symbol

KLRC4

UniProt

NP_038459.1

Additional KLRC4 Products

Product Documents for Human KLRC4/NKG2F (NP_038459.1) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human KLRC4/NKG2F (NP_038459.1) VersaClone cDNA

For research use only

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