Human Lambda5/IGLL1 (NP_064455) VersaClone cDNA

R&D Systems | Catalog # RDC1559

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Key Product Details

Species

Human

Accession Number

NP_064455

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Lambda5/IGLL1

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Immunoglobulin Lambda-Like Polypeptide 1

Alternate Names

AGM2, CD179b, IGL5, IGLJ14.1, IGLL1, IGO, IGVPB, VPREB2

Entrez Gene IDs

3543 (Human); 16136 (Mouse); 100360919 (Rat)

Gene Symbol

IGLL1

UniProt

NP_064455

Additional Lambda5/IGLL1 Products

Product Documents for Human Lambda5/IGLL1 (NP_064455) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human Lambda5/IGLL1 (NP_064455) VersaClone cDNA

For research use only

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