Human Latrophilin 2/LPHN2 (NP_036434) VersaClone cDNA

Name: Human Latrophilin 2/LPHN2 (NP_036434) VersaClone cDNA
Brand: R&D Systems
SKU: RDC0800

R&D Systems | Catalog # RDC0800

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Discontinued Product

RDC0800 has been discontinued. View all Latrophilin 2/LPHN2 products.

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Product Documents
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Key Product Details

Species

Human

Accession Number

NP_036434

Background: Latrophilin 2/LPHN2

Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covantely linked as a heterodimer. Latrophilin-2 has been reported to be expressed in brain, breast, placenta, kidney, spleen, ovary, heart, and lung. ESTs have been isolated from a wide variety of tissue libraries.

Long Name

Latrophilin 2

Alternate Names

ADGRL2, CIRL2, LEC1, LPHH1, LPHN2

Entrez Gene IDs

23266 (Human)

Gene Symbol

ADGRL2

UniProt

NP_036434

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Product Specific Notices for Human Latrophilin 2/LPHN2 (NP_036434) VersaClone cDNA

For research use only

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