Latrophilin-3 (LPHN3) is a 7-TM adhesion GPCR with a large N-terminal extracellular region. It is expressed in the brain cortex and binds to FLRT1, 2, and 3 and Tenurin 1. Its binding in trans to post-synaptic FLRT3 at glutamatergic synapses supports the maintenance of excitatory synapses as well as the amplitude of glutamatergic transmission. Polymorphisms of Latrophilin-3 are associated with susceptibility to attention deficit/hyperactivity disorder (ADHD).
Human Latrophilin 3/LPHN3 (NP_056051) VersaClone cDNA
R&D Systems | Catalog # RDC2131
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Background: Latrophilin 3/LPHN3
Alternate Names
CIRL3, LEC3, Lectomedin-3, LPHN3
Gene Symbol
ADGRL3
UniProt
Additional Latrophilin 3/LPHN3 Products
Product Documents for Human Latrophilin 3/LPHN3 (NP_056051) VersaClone cDNA
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Product Specific Notices for Human Latrophilin 3/LPHN3 (NP_056051) VersaClone cDNA
For research use only
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