LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C, also called NGL-2 (netrin-G ligand-2), NGL-3 and NGL-1, respectively, are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. Mature LRRC4 family members are type I transmembrane proteins with an extracellular region that contains nine LRRs, a C2-type Ig-like domain, and a Thr-rich segment. LRRC4 family members share ~55% aa identity, but each recognizes different ligands. LRRC4 and LRRC4C recognize Netrin-G2 and Netrin-G3, respectively, while LRRC4B recognizes the receptor tyrosine phosphatases LAR/PTPRF, PTPR delta and PTPR sigma.
Human LRRC4 (NP_071426) VersaClone cDNA
R&D Systems | Catalog # RDC1713
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: LRRC4
Long Name
Leucine-rich Repeat Containing 4
Alternate Names
BAG, NAG14
Gene Symbol
LRRC4
UniProt
Additional LRRC4 Products
Product Documents for Human LRRC4 (NP_071426) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human LRRC4 (NP_071426) VersaClone cDNA
For research use only
Related Research Areas
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