Human matriptase, encoded by the ST14 (suppression of tumorogenicity 14) gene, is also known as tumor associated differentially expressed gene 15 protein/TADG-15), epithin, and membrane-type serine protease 1/MT-SP1. Predicted to have a significant role in tumor biology, matriptase may be a novel target for anti-cancer therapy. However, expressed in most human epithelia, matriptase is also important in several physiological processes. For example, it activates prostasin to initiate a protease cascade that is essential for epidermal differentiation, and it converts a single-chain IGFBP-rp1 into the two-chain form.
Human Matriptase/ST14 (NP_068813) VersaClone cDNA
R&D Systems | Catalog # RDC2469
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Matriptase/ST14
Alternate Names
Epithin, MTSP1, PRSS14, SNC19, ST14, TADG-15, TMPRSS14
Gene Symbol
ST14
UniProt
Additional Matriptase/ST14 Products
Product Documents for Human Matriptase/ST14 (NP_068813) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human Matriptase/ST14 (NP_068813) VersaClone cDNA
For research use only
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