human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

Name: human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3632
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC3632

Submit a review

Product Documents

100% Guarantee

Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_003782.1

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: MBTPS1/SKI-1

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Long Name

Membrane Bound Transcription Factor Peptidase, Site 1

Alternate Names

KIAA0091, PCSK8, S1P, SEDKF, SKI-1

Entrez Gene IDs

8720 (Human)

Gene Symbol

MBTPS1

UniProt

NP_003782.1

Additional MBTPS1/SKI-1 Products

Product Documents for human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

For research use only

Related Research Areas

Serine Proteases and Regulators

Customer Reviews for human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA

There are currently no reviews for this product. Be the first to review human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA and earn rewards!

Have you used human MBTPS1/SKI-1 (NP_003782.1) VersaClone cDNA?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image