Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
Human Mcl-1 (NP_068779.1) VersaClone cDNA
R&D Systems | Catalog # RDC3059
Loading...
Loading...
Background: Mcl-1
Long Name
Myeloid Cell Leukemia Sequence 1
Alternate Names
BCL2L3, Mcl1
Gene Symbol
MCL1
UniProt
Additional Mcl-1 Products
Product Documents for Human Mcl-1 (NP_068779.1) VersaClone cDNA
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Mcl-1 (NP_068779.1) VersaClone cDNA
For research use only
Related Research Areas
Customer Reviews for Human Mcl-1 (NP_068779.1) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human Mcl-1 (NP_068779.1) VersaClone cDNA and earn rewards!
Have you used Human Mcl-1 (NP_068779.1) VersaClone cDNA?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...
Associated Pathways
