Human MDR3/ABCB4 (NP_061338) VersaClone cDNA

Name: Human MDR3/ABCB4 (NP_061338) VersaClone cDNA
Brand: R&D Systems
SKU: RDC0946
Price: 1079 USD
Availability: InStock

R&D Systems | Catalog # RDC0946

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Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_061338

Background: MDR3/ABCB4

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. (provided by RefSeq)

Long Name

Multiple Drug Resistance 3

Alternate Names

ABC21, ABCB4, GBD1, PFIC-3, PGY3

Entrez Gene IDs

5244 (Human); 18670 (Mouse); 24891 (Rat)

Gene Symbol

ABCB4

UniProt

NP_061338

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Product Specific Notices for Human MDR3/ABCB4 (NP_061338) VersaClone cDNA

For research use only

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