Human MMP-15/MT2-MMP Alexa Fluor® 750-conjugated Antibody

  
  • Species Reactivity
    Human
  • Specificity
    Detects human MMP‑15/MT2‑MMP in direct ELISAs and Western blots. Does not detect the catalytic domain of E. coli-expressed recombinant human MMP-15 (aa 132‑304).
  • Source
    Monoclonal Mouse IgG1 Clone # 130522
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant human MMP-15
    aa 132-625
  • Formulation
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
  • Label
    Alexa Fluor 750
Applications
  •  
    Recommended
    Concentration
    Sample
  • Intracellular Staining by Flow Cytometry
    0.25-1 µg/106 cells
    SW480 human colorectal adenocarcinoma cell line fixed with paraformaldehyde and permeabilized with saponin
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: MMP-15/MT2-MMP
MMP-15, also known as membrane-type 2 (MT2) MMP, is a cell surface endopeptidase that plays a role in tumor invasion and metastasis.
  • Long Name:
    Matrix Metalloproteinase 15/Membrane Type 2 MMP
  • Entrez Gene IDs:
    4324 (Human)
  • Alternate Names:
    EC 3.4.24; EC 3.4.24.-; EC 3.4.24.80; matrix metallopeptidase 15 (membrane-inserted); matrix metalloproteinase 15 (membrane-inserted); Membrane-type matrix metalloproteinase 2; Membrane-type-2 matrix metalloproteinase; MMP15; MMP-15; MT2-MMP; MT2-MMPMT2MMP; MTMMP2MT-MMP 2; SMCP-2matrix metalloproteinase-15
Related Research Areas

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