Human/Mouse LPP Alexa Fluor™ Plus 594‑conjugated Antibody

R&D Systems | Catalog # FAB6927AFP594

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Alexa Fluor Plus 594 (Excitation = 590 nm, Emission = 618 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 691121
View all LPP Primary Antibodies »

Product Specifications

Specificity

Detects human LPP in direct ELISAs.  In direct ELISAs, no cross-reactivity with recombinant human TRIP-4, -6, or -11 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human/Mouse LPP Alexa Fluor™ Plus 594‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: LPP

Human LIM domain-containing preferred translocation partner in lipoma (LPP) is an 80 kDa intracellular protein that contains an N-terminal Pro-rich region (aa 41-370) followed by three tandem LIM domains (aa 414-603). It localizes to focal adhesion plaques where it regulates junction assembly and cytoskeleton remodeling through interactions with a-Actinin, VASP, SCRIB, Supervillin, and Palladin. In the nucleus, LPP coactivates the transcription factor PEA3 and protects telomeres from DNA damage. LPP is a frequent target of chromosomal translocations with HMG-A2 in lipoma. Within aa 138-261, human LPP shares 90% and 77% aa sequence identity with mouse and rat LPP, respectively.

Long Name

Lipoma-Preferred Partner

Alternate Names

DKFZp779O0231, FLJ30652, FLJ41512, LIM domain containing preferred translocation partner in lipoma, LIM domain-containing preferred translocation partner in lipoma, LIM protein, lipoma-preferred partner

Entrez Gene IDs

4026 (Human); 210126 (Mouse); 288010 (Rat)

Gene Symbol

LPP

UniProt

Q93052

Additional LPP Products

Product Documents for Human/Mouse LPP Alexa Fluor™ Plus 594‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human/Mouse LPP Alexa Fluor™ Plus 594‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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