OMgp is a GPI-anchored protein derived from myelin. It is expressed on oligodendrocytes and neurons and binds to a receptor complex consisting of the Nogo receptor and the p75 neurotrophin receptor, NGF R. OMgp is active in the inhibition of axonal outgrowth as well as regeneration following injury.
Human/Mouse OMgp Antibody
R&D Systems | Catalog # MAB1674
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Mouse
Applications
Validated:
Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG1 Clone # 240527
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse OMgp
Ile25-Ser420
Accession # Q63912
Ile25-Ser420
Accession # Q63912
Specificity
Detects human and mouse OMgp in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human OMgp is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG1
Applications for Human/Mouse OMgp Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human OMgp (Catalog # 1673-OM)
Recombinant Mouse OMgp (Catalog # 1674-MG)
Sample: Recombinant Human OMgp (Catalog # 1673-OM)
Recombinant Mouse OMgp (Catalog # 1674-MG)
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: OMgp
Long Name
Oligodendrocyte-Myelin glycoprotein
Alternate Names
OMG
Gene Symbol
OMG
UniProt
Additional OMgp Products
Product Documents for Human/Mouse OMgp Antibody
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human/Mouse OMgp Antibody
For research use only
Related Research Areas
Citations for Human/Mouse OMgp Antibody
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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