Home / alpha Actinin 1 / Human/Mouse/Rat alpha -Actinin 1 Alexa Fluor® 594-conjugated Antibody

Human/Mouse/Rat alpha -Actinin 1 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB8279T Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB8279T-100UG

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Human/Mouse/Rat alpha -Actinin 1 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human alpha -Actinin 1 in ELISA, and human, mouse and rat alpha -Actinin 1 in Western Blot.
Source
Monoclonal Mouse IgG2b Clone # 910301
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human Î±-Actinin 1 
Asn272-Thr500
Accession # P12814
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: alpha Actinin 1

alpha -Actinin 1 (ACTN1) is a member of the spectrin superfamily with a predicted molecular weight of approximately 100 kDa.  It is 892 amino acids (aa) in length and shares 99% aa identity with mouse and rat ACTN1.  Multiple splice forms exist, resulting in 4 distinct isoforms with different tissue expression patterns.  ACTN1 binds to F-actin as well as other cytoskeletal and signaling proteins and plays an important role in both cell motility and muscle contraction.

Long Name
Actinin alpha 1
Entrez Gene IDs
87 (Human); 109711 (Mouse); 81634 (Rat)
Alternate Names
actinin 1 smooth muscle; actinin, alpha 1; ACTN1; alpha Actinin 1; alphaActinin 1; alpha-Actinin 1; Alpha-actinin cytoskeletal isoform; alpha-actinin-1; BDPLT15; F-actin cross-linking protein; FLJ40884; FLJ54432; Non-muscle alpha-actinin-1

Product Datasheets

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