Alpha-Internexin ( alpha -INX; also 66 kDa neurofilament protein (NF-66)) is a 66 kDa member of the intermediate filament (IF) protein family. It was the first of two molecules named for its presumed interaction with cytoskeletal proteins. alpha -INX is one of four Class IV neuronal IF proteins. It both self-assembles, and complexes with NF-L, H and M in select cortical and cerebellar neurons. Human alpha -INX is 499 amino acids (aa) in length. It has a predicted MW of 55 kDa, but runs anomalously at 66 kDa in SDS-PAGE. alpha -INX contains one DNA-binding region (aa 10‑92), a poly-Glu segment (aa 449‑454) and three serine phosphorylation sites (Ser72/335/496). There is one 494 aa alternative splice form that shows multiple short sequence aa substitutions in the first 200 amino acids. Over aa 230‑450, human alpha -INX shares more that 96% aa identity with mouse, canine and rat alpha -INX.
Human/Mouse/Rat alpha-Internexin Alexa Fluor® 594‑conjugated Antibody
R&D Systems | Catalog # AF4844T
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Val230-Glu450
Accession # Q16352
Specificity
Clonality
Host
Isotype
Applications for Human/Mouse/Rat alpha-Internexin Alexa Fluor® 594‑conjugated Antibody
Western Blot
Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
Background: alpha-Internexin
Alternate Names
Gene Symbol
UniProt
Additional alpha-Internexin Products
Product Documents for Human/Mouse/Rat alpha-Internexin Alexa Fluor® 594‑conjugated Antibody
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human/Mouse/Rat alpha-Internexin Alexa Fluor® 594‑conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only
Related Research Areas
Customer Reviews
There are currently no reviews for this product. Be the first to review Human/Mouse/Rat alpha-Internexin Alexa Fluor® 594‑conjugated Antibody and earn rewards!
Have you used Human/Mouse/Rat alpha-Internexin Alexa Fluor® 594‑conjugated Antibody?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars