Human/Mouse/Rat FKBP52 Alexa Fluor® 532-conjugated Antibody

Catalog #: AF4095X Datasheet / COA / SDS

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AF4095X-100UG

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All FKBP52 Antibodies

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Human/Mouse/Rat FKBP52 Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects endogenous human, mouse and rat FKBP52 in Western blots. In Western blots, this antibody does not cross-react with recombinant human FKBP12, FKBP13, FKBP38 or FKBP51.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human FKBP52
Met1-Ala459
Accession # Q02790

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FKBP52

FK506 binding protein, 52 kDa molecular weight (FKBP52), also called FKBP4, is a peptidyl-prolyl isomerase that catalyzes the transition between cis- and trans- proline residues critical for proper folding of proteins. It associates with HSP90 complexes that are critical for the proper folding of steroid receptors. FKBP52 knockout mice have abnormal reproductive organ development due to disruption of androgen receptor folding.

Long Name

52 kDa FK506 Binding Protein

Entrez Gene IDs

2288 (Human); 14228 (Mouse); 260321 (Rat)

Alternate Names

51 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; EC 5.2.1.8; FK506 binding protein 4, 59kDa; FK506-binding protein 4 (59kD); FK506-binding protein 4; FKBP4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52T-cell FK506-binding protein, 59kD; FKBP59; FKBP5952 kDa FK506-binding protein; HBI; HSP binding immunophilin; Hsp56; HSP-binding immunophilin; Immunophilin FKBP52; p52; p59; peptidyl-prolyl cis-trans isomerase FKBP4; peptidylprolyl cis-trans isomerase; PPIase FKBP4; PPIase; rotamase