NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
GRIN1/NMDAR1 Antibody (R1JHL)
R&D Systems | Catalog # PPS011B
Discontinued Product
PPS011B has been discontinued.
View all GRIN1/NMDAR1 products.
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat
Cited:
Mouse, Transgenic Mouse
Applications
Validated:
Western Blot, Immunoprecipitation
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG Clone # R1JHL
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Product Specifications
Immunogen
NMDA R, NR1 Subunit
Clonality
Monoclonal
Host
Mouse
Isotype
IgG
Applications for GRIN1/NMDAR1 Antibody (R1JHL)
Application
Recommended Usage
Immunoprecipitation
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Formulation
Lyophilized from cell culture media
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: GRIN1/NMDAR1
Long Name
Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate, Subunit 1
Alternate Names
GluN1, MRD8, NMD-R1, NMDA R, NR1 Subunit, NMDA1, NMDAR1
Gene Symbol
GRIN1
Additional GRIN1/NMDAR1 Products
Product Documents for GRIN1/NMDAR1 Antibody (R1JHL)
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for GRIN1/NMDAR1 Antibody (R1JHL)
For research use only
Citations for GRIN1/NMDAR1 Antibody (R1JHL)
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- Immunoprecipitation Protocol
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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